«The shooter has been eliminated!!! The entire building is currently being evacuated and there are several dead and dozens of injured,» police said on X, formerly Twitter.
The police urged citizens who stay in the immediate vicinity «not to leave the house» saying that police intervention is still ongoing.
«Based on initial information, we can confirm that there are dead and injured people at the scene,» it added.
Media reports, citing local agencies, said that e shooting had occurred at the Charles University Faculty of Arts whose teachers and students were instructed to lock themselves up as police action was under way.
The private Nova TV reported a blast and a gunman on the roof of the building in Prague's historic centre.
Interior Minister Vit Rakusan told the public Czech TV «no other gunman has been confirmed» and called on people to follow police instructions.
Police closed the area and asked people living nearby to stay at home.