Shares of Biocon Ltd.(up 2.32 per cent) and Alkem Laboratories Ltd.(up 0.46 per cent) ended the day as top gainers in the pack.
On the other hand, Aurobindo Pharma Ltd.(down 2.68 per cent), Divi's Laboratories Ltd.(down 2.44 per cent), Glenmark Pharmaceuticals Ltd.(down 2.34 per cent), Pfizer Ltd.(down 2.11 per cent) and Natco Pharma Ltd.(down 1.97 per cent) finished as the top losers of the day.
The Nifty Pharma index closed 1.14 per cent down at 17320.15.
Benchmark NSE Nifty50 index ended down 65.16 points at 22032.3, while the BSE Sensex stood down 199.17 points at 73128.77.
Among the 50 stocks in the Nifty index, 16 ended in the green, while 34 closed in the red.
Shares of YES Bank, Indian Railway Fin, Vodafone Idea, South Indian Bnk and JP Power were among the most traded shares on the NSE.
Shares of ITI Ltd, Capri Global, Newgen Software, Vaishali Pharma and Rane Eng Valve hit their fresh 52-week highs in today's trade, while M K Proteins, Digidrive Distributo, Muthoot Microfin, Raj Rayon and GSS Infotech hit their fresh 52-week lows.