A blood test for colon cancer performed well in a study, expanding options for screening
A blood test for colon cancer performed well in a study, offering a new kind of screening
A blood test for colon cancer performed well in a study published Wednesday, offering a new kind of screening for a leading cause of cancer deaths.
The test looks for DNA fragments shed by tumor cells and precancerous growths. It's already for sale in the U.S. for $895, but has not been approved by the Food and Drug Administration and most insurers do not cover it. The maker of the test, Guardant Health, anticipates an FDA decision this year.
In the study, the test caught 83% of the cancers but very few of the precancerous growths found by colonoscopy, the gold standard for colon cancer screening. Besides spotting tumors, colonoscopies can prevent the disease by removing precancerous growths called polyps.
But some people avoid the exam because of the hassle of getting time off work or the day-ahead preparation that involves drinking a strong laxative to empty the bowels.
A convenient alternative is an annual stool test, where people send a stool sample to a lab for analysis.
“The best test is the one someone will actually complete,” said Dr. Douglas Corley, chief research officer for Kaiser Permanente, Northern California, who was not involved in the study. “Giving people a choice increases the number of people who will get screened.”
In the U.S., screening is recommended for healthy adults ages 45 to 75 at average risk for colon cancer. Frequency depends on the test: a routine colonoscopy is every 10 years. Screening is inching up but falls well short of the 80% of age-eligible adults goal set by the American Cancer Society and other groups.
Guardant recommends testing with its blood test called Shield every three years. Like
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