New Delhi, A coalition of institutions from dengue-endemic countries aims to deliver a new treatment for dengue from repurposed drugs and combinations within 5 years, according to a comment published in The Lancet Global Health journal. The mission of the alliance, The Dengue Alliance, is to accelerate research and development and deliver dengue therapeutics through an inclusive partnership, it said.
«An integrated approach that comprises vector control, use of safe and effective vaccines, and an effective treatment is needed to face the growing challenges of dengue infection,» the alliance formed by the Drugs for Neglected Diseases initiative (DNDi), Switzerland, said in its comment.
The DNDi, founded in 2003, is an international, not-for-profit research and development organisation developing new affordable and patient-friendly treatments for neglected tropical diseases.
The Dengue Alliance, launched in 2022, is co-created, co-owned, and co-funded by dengue-endemic countries, and includes the Translational Health Science and Technology Institute in India, along with institutions from Brazil, Malaysia and Thailand. Dengue, a global public health threat, is a climate-sensitive neglected tropical disease and currently the most rapidly spreading mosquito-borne viral infection in the world.
It is estimated to infect approximately 390 million individuals annually, with 96 million infections being symptomatic, the comment said.
The Dengue Alliance attributed the rapidly increasing incidence of dengue to climate change,