Restoring vision: Groundbreaking procedure uses stem cells to treat eye injuries

economictimes.indiatimes.com:

eye bore the brunt of the 2017 work accident, which stole his vision, left him unable to tolerate light and triggered four to five cluster headaches a day. Then he underwent an experimental procedure that aims to treat severe injuries in one eye with stem cells from the other. «I went from completely blind with debilitating headaches and pondering if I could go another day — like really thinking I can't do this anymore» to seeing well enough to drive and emerging from dark places literally and figuratively, he said, choking up. The 51-year-old from Homewood, Alabama, was one of four patients to get stem cell transplants as part of the first U.S. study to test the technique, which could someday help thousands. Though additional treatment is sometimes needed, experts say the stem cell transplant offers hope to people with few if any other options. Results of the early-stage research were published Friday in the journal Science Advances, and a larger study is now underway.

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The procedure is designed to treat «limbal stem cell deficiency,» a corneal disorder that can occur after chemical burns and other eye injuries. Patients without limbal cells, which are essential for replenishing and maintaining the cornea's outermost layer, can't undergo corneal transplants that are commonly used to improve vision. Dr. Ula Jurkunas, an ophthalmologist at Mass Eye and Ear in Boston who was the principal investigator for the study, said the experimental technique involves taking a small biopsy of stem cells from the healthy eye, then expanding and growing them on a graft in a lab at Dana-Farber Cancer Institute in Boston. A couple of weeks later,