diabetes patient using cell transplants, reports said on September 30. The landmark surgery, which marks a world's first, lasted just half an hour, news agency PTI reported citing The Paper, a Shanghai-based news outlet.
The patient, a 25-year-old woman, began naturally regulating her blood sugar levels approximately two and a half months after the procedure, the reports said.
Researchers from Tianjin First Central Hospital and Peking University were part of the team that published their findings in the peer-reviewed journal Cell last week.
Traditionally, islet transplants involve taking islet cells from a deceased donor's pancreas and placing them in the liver of a type 1 diabetes patient. This method is effective but limited by donor shortages. Islet cells are crucial for regulating blood sugar as they produce hormones like insulin and glucagon.
The new treatment used «chemically induced pluripotent stem-cell-derived islets» or CiPSC islets. To achieve this, researchers collected adipose tissue cells from the patient and reprogrammed them into pluripotent stem cells using small molecule chemicals. These cells were then transformed into islet cells and transplanted back into the patient. Because the cells were derived from the patient's body, there was no immune rejection.
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