Domestic benchmark index NSE Nifty ended 82.05 points down at 19542.65, while the BSE Sensex closed 231.62 points down at 65397.62.
On the other hand, Dhunseri Invst, Bombay Burmah, GKW Ltd, Summit Sec and Prajay Engg stocks hit their fresh 52-week highs today.
In the Nifty 50 index, Kotak Bank, IndusInd Bank, TCS, SBI Life and NTPC were among the top gainers on the NSE in the today's trade.
Meanwhile, ITC, Tata Steel, Divis Labs, HUL and BPCL were among the top losers of the day.