Domestic benchmark index NSE Nifty fell 286.35 points to 21745.95, while the BSE Sensex traded 1021.63 points down at 72107.14.
On the other hand, Goa Carbons, Shemaroo Entertain, Century Extrus, Cochin Shipyard and Rane Eng Valve stocks hit their fresh 52-week highs today.
In the Nifty 50 index, TCS, HCL Tech, Apollo Hospital, Hero MotoCorp and HDFC Life were among the top gainers on the NSE.
HDFC Bank, Kotak Bank, Tata Steel, Hindalco and Bajaj Auto were among the top losers.