Domestic benchmark index NSE Nifty ended 140.4 points down at 19671.1, while the BSE Sensex closed 551.07 points down at 65877.02.
On the other hand, GKW Ltd, Cinevista Ltd, Signet Ind, IIFL Securities and Sastasundar Ventures stocks hit their fresh 52-week highs today.
In the Nifty 50 index, Cipla, Dr. Reddys, Tata Motors, Sun Pharma and SBI Life were among the top gainers on the NSE in the today's trade.