Domestic benchmark index NSE Nifty fell 104.65 points to 19566.45, while the BSE Sensex traded 362.95 points down at 65514.07.
On the other hand, Shakti Pumps, GKW Ltd, DB(Intl)Stock, PNB Gilts and Jindal Poly Investm stocks hit their fresh 52-week highs today.
In the Nifty 50 index, LTIMindtree, Bajaj Auto, IndusInd Bank, Hero MotoCorp and BPCL were among the top gainers on the NSE.
Wipro, Coal India Ltd, UPL, Hindalco and Cipla were among the top losers.