Australian scientist confirm 100-year-old theory, discover new cell type that can heal chronic injuries

economictimes.indiatimes.com:

SAHMRI) and the University of Adelaide have announced the discovery of a previously unknown cell type called EndoMac progenitors. This finding, a result of nine years of dedicated research, fills a crucial gap in the understanding of how mammals heal. It could pave the way for new treatment options for chronic conditions, particularly diabetes.

Characteristics of EndoMac Progenitors

EndoMac progenitor cells were identified in the outer layer of the aortas of adult mice. These cells possess the unique ability to transform into two types of important cells: endothelial cells, which help form blood vessels, and macrophages, which are immune cells responsible for tissue repair and defense. Dr. Sanuri Liyanage from SAHMRI stated, «The EndoMac progenitor cells possess the unique ability to transform into two specific cell types of cells: endothelial cells that form blood vessels and macrophages that are immune cells responsible for tissue repair and defence.» She elaborated, «These cells have an important job: to help grow blood vessels when the body calls for it.» Furthermore, Dr. Liyanage mentioned, «They are activated by injury or poor blood flow, at which point they rapidly expand to aid in healing.»

Implications for Human Health

The implications of the discovery of EndoMac progenitor cells could be revolutionary for treatments in humans. Because these cells do not express typical «self» markers, they are less likely to be attacked by the immune system, making them ideal candidates for stem cell therapy. Ongoing research suggests that these cells could significantly improve healing in conditions like diabetes, where the body struggles to repair itself effectively. According to the researchers, the cells showed remarkable