Sildenafil, known by its brand name Viagra, may have benefits beyond treating erectile dysfunction. Recent research suggests it can help prevent memory-related problems by increasing cerebral blood flow and enhancing blood vessel function in those at risk of vascular dementia, a TOI report by Anuja Jaiswal stated.
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Vascular dementia impacts cognitive functions like memory, reasoning, and judgment due to reduced blood supply to the brain, which damages brain tissue. This condition differs from Alzheimer's disease, where cognitive dysfunction is caused by amyloid beta plaques blocking neuron connectivity. In vascular dementia, obstructions in blood vessels lead to brain cell damage.
A study by University of Oxford scientists, published in the journal Circulation Research, marks a significant step in the fight against dementia. Dr. Praveen Gupta, principal director of neurology at Fortis Gurgaon, told TOI that these findings could be crucial in developing treatments for dementia. However, he emphasized the need for larger studies to confirm sildenafil's effectiveness before it could be adopted as a standard treatment.
In India, the burden of vascular cognitive impairment and dementia is substantial, with about 5.3 million dementia patients, 40%
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